Low Level Whole-Brain Radiation Enhances Theranostic Potential Of Single Domain Antibody Fragments For HER2-Positive Brain Metastases
D. Procissi, S. Jannetti, M. Zannikou, Z. Zhou, D. McDougald, D. Kanojia, G. Vaidyanathan, M. R. Zalutsky, I. V. Balyasnikova
This study shows that low-dose whole-brain irradiation increases the uptake of an anti-HER2 VHH in intracranial tumors, enhancing its theranostic potential for HER2-positive brain metastases.
bioRxiv · Apr 19, 2022Cancer Biology