Site-specific phosphorylation of PSD-95 dynamically regulates the post-synaptic density as observed by phase separation
M. Vistrup-Parry, X. Chen, T. Johansen, S. Bach, S. Buch-Larsen, C. Bartling, C. Ma, L. Clemmensen, M. L. Nielsen, M. Zhang, K. Stromgaard
The paper introduces site-specific phosphorylations in PSD-95 and shows how they affect phase separation with interaction partners, revealing opposing effects on condensate formation.
bioRxiv · Mar 3, 2021 · PreprintBiochemistry