Author

C. Bladen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:electrophysiology· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. Connor· 3 shared M. Santiago· 3 shared S. Banister· 2 shared S. Mirlohi· 2 shared M. ` Kassiou· 1 shared M. Kassiou· 1 shared M. Longworth· 1 shared S. Sachdev· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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3 shared papersPharmacology & Toxicology

M. Connor

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3 papers

Recent·Most cited

Modulation of Recombinant Human T-type calcium channels by Δ9-tetrahydrocannabinolic acid in vitro

S. Mirlohi, C. Bladen, M. Santiago, M. Connor

This study investigates the effects of THCA on T-type calcium channels in vitro, finding it modulates channel kinetics and voltage dependence without psychoactive effects.

bioRxiv · Oct 11, 2020Pharmacology & Toxicology

Modulation of Human T-type Calcium Channels by Synthetic Cannabinoid Receptor Agonists in vitro

C. Bladen, S. Mirlohi, M. Santiago, M. Longworth, M. Kassiou, S. Banister, M. Connor

This study investigates how synthetic cannabinoid receptor agonists modulate human T-type calcium channels, finding potent inhibition and suggesting a potential mechanism for their toxicity.

bioRxiv · Jul 22, 2020Pharmacology & Toxicology

Differential activation of G protein-mediated signalling by synthetic cannabinoid receptor agonists

S. Sachdev, S. Banister, M. Santiago, C. Bladen, M. ` Kassiou, M. Connor

This study compares how synthetic cannabinoid receptor agonists activate Gs and Gi/o proteins, finding differences in their potency and rank order for cAMP stimulation and inhibition.

bioRxiv · Nov 22, 2019 · PreprintPharmacology & Toxicology