M. Santiago

This study shows that (-)-cannabichromene activates CB2 receptors, while (+)-cannabichromene does not, and both activate TRPA1.

This study identifies genes essential for Staphylococcus aureus growth at low pH, highlighting histidine transport's role in maintaining intracellular pH.

This study investigates the effects of THCA on T-type calcium channels in vitro, finding it modulates channel kinetics and voltage dependence without psychoactive effects.

This study investigates how synthetic cannabinoid receptor agonists modulate human T-type calcium channels, finding potent inhibition and suggesting a potential mechanism for their toxicity.

This paper identifies a hydrolase complex in Staphylococcus aureus that releases peptidoglycan from the membrane by cleaving nascent polymers, enabling their integration into the cell wall matrix.

This study uses TN-seq to analyze osmotic stress responses in S. aureus, identifying gene 957 as essential under salt stress and highlighting the role of cell wall crosslinking in osmotic resistance.

This study compares how synthetic cannabinoid receptor agonists activate Gs and Gi/o proteins, finding differences in their potency and rank order for cAMP stimulation and inhibition.