Author

C. Blakely

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Urisman· 1 shared D. Tan· 1 shared F. Haderk· 1 shared J. Rotow· 1 shared J. Shue· 1 shared J. Suzuki· 1 shared L. Kerr· 1 shared M. Mayekar· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Urisman

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1 paper

Recent·Most cited

Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR mutant lung cancer

S. Nanjo, W. Wu, N. Karachaliou, C. Blakely, J. Suzuki, S. Ali, L. Kerr, V. Olivas, J. Shue, J. Rotow, M. Mayekar, F. Haderk, N. Chatterjee, A. Urisman, Y. Kirichok, , T. Bivona

This study shows that RBM10 deficiency reduces EGFR inhibitor efficacy in EGFR mutant lung cancer by altering Bcl-x splicing and apoptosis, and that co-inhibiting Bcl-xL can overcome this resistance.

bioRxiv · Oct 26, 2020 · PreprintCancer Biology