Author

C. Browne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. A. Cowley· 3 shared W. S. James· 2 shared A. T. Hanrath· 1 shared A. Taylor· 1 shared A. Vaughan-Jackson· 1 shared B. T. Selvaraj· 1 shared C. F. Hatton· 1 shared C. J. A. Duncan· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

S. A. Cowley

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Author profile →

3 papers

Recent·Most cited

Type I interferons govern Zika virus resistance of human macrophages and microglia

A. T. Hanrath, C. F. Hatton, F. Gothe, C. Browne, J. Vowles, P. Leary, S. J. Cockell, S. A. Cowley, W. S. James, S. Hambleton, C. J. A. Duncan

This study shows that type I interferons restrict Zika virus replication in macrophages and microglia, and their suppression increases viral replication and cell damage.

bioRxiv · Mar 9, 2022 · PreprintCell Biology

Differentiation of Human induced Pluripotent Stem Cells to Authentic Macrophages using Fully Defined, Serum Free, Open Source Media

A. Vaughan-Jackson, S. Stodolak, K. H. Ebrahimi, C. Browne, P. K. Reardon, E. Pires, J. Gilbert-Jaramillo, S. A. Cowley, W. S. James

This paper describes two fully defined, serum-free, open-source media for culturing human iPSCs and differentiating them into macrophages, showing improved characteristics compared to commercial media.

bioRxiv · Oct 27, 2020Immunology

Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936

J. Toombs, L. Panther, L. Ornelas, C. Liu, E. Gomez, R. Martinibanez, S. R. Cox, S. J. Ritchie, S. E. Harris, A. Taylor, P. Redmond, T. C. Russ, L. Murphy, J. D. Cooper, K. Burr, , D. Sareen

The paper generates 24 induced pluripotent stem cell lines from members of the Lothian Birth Cohort 1936 to study cognitive ageing and neurodegenerative disease resilience.

bioRxiv · Feb 5, 2020Cell Biology