Author

E. Pires

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. McCullagh· 2 shared A. A. Ahmed· 1 shared A. Coosemans· 1 shared A. Easton· 1 shared A. L. Harris· 1 shared A. Pielach· 1 shared A. Vaughan-Jackson· 1 shared B. Kessler· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

J. McCullagh

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Analysis of the influence of peptidoglycan turnover and recycling on host-pathogen interaction in the Gram-positive pathogen Staphylococcus aureus

J. Dorling, M. D. Atilano, E. Pires, E. Johnson, A. Pielach, J. McCullagh, S. R. Filipe, P. Ligoxygakis

This study investigates the role of peptidoglycan turnover and recycling in S. aureus host-pathogen interaction, showing that impaired recycling affects virulence and immune activation in Drosophila.

bioRxiv · Jul 3, 2023 · PreprintMicrobiology

LARP1 regulates metabolism and mTORC1 activity in cancer

J. Chettle, Z. Dedeic, R. Fischer, I. Vendrell, L. Campo, A. Easton, M. Browne, J. Morris, H. Schwenzer, P. Lascaux, R. Gijsbers, E. Pires, D. J. Royston, D. J. P. Ferguson, A. Coosemans, , S. P. Blagden

This study identifies LARP1 as a key regulator of metabolism and mTORC1 activity in cancer, showing its role in sustaining cellular metabolism and driving cancer progression.

bioRxiv · Sep 4, 2022 · PreprintCancer Biology

RAD51AP1 mediates RAD51 activity through nucleosome interaction

E. Pires, N. Sharma, P. Selemenakis, B. Wu, Y. Huang, D. Alimbetov, W. Zhao, C. Wiese

This study shows RAD51AP1 binds nucleosomes and aids RAD51 in chromatin-mediated DNA repair by facilitating donor DNA capture and joint-molecule formation.

bioRxiv · Dec 17, 2020Biochemistry

Differentiation of Human induced Pluripotent Stem Cells to Authentic Macrophages using Fully Defined, Serum Free, Open Source Media

A. Vaughan-Jackson, S. Stodolak, K. H. Ebrahimi, C. Browne, P. K. Reardon, E. Pires, J. Gilbert-Jaramillo, S. A. Cowley, W. S. James

This paper describes two fully defined, serum-free, open-source media for culturing human iPSCs and differentiating them into macrophages, showing improved characteristics compared to commercial media.

bioRxiv · Oct 27, 2020Immunology