Author

C. Cambier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:zebrafish· 3 Assay:imaging· 2 Organism:mouse· 1

Frequent Co-Authors

C. Bertozzi· 2 shared D. B. Moody· 2 shared T.-Y. Cheng· 2 shared A. Sagasti· 1 shared B. R. Bloom· 1 shared C. A. Madigan· 1 shared J. A. Buonomo· 1 shared J. Zailaa· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

C. Bertozzi

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Author profile →

3 papers

Recent·Most cited

Bioorthogonal metabolic labeling of the virulence factor phenolic glycolipid in mycobacteria

L. E. Guzman, C. Cambier, T.-Y. Cheng, K. F. Naqvi, M. U. Shiloh, D. B. Moody, C. Bertozzi

The paper develops a method to image phenolic glycolipid (PGL) in mycobacteria using bioorthogonal metabolic labeling and demonstrates its application in studying PGL dynamics.

bioRxiv · Nov 28, 2023Biochemistry

Spreading of a mycobacterial cell surface lipid into host epithelial membranes promotes infectivity

C. Cambier, S. Banik, J. A. Buonomo, C. Bertozzi

This study shows that PDIM from mycobacteria spreads into host epithelial membranes, inhibiting TLR activation and enhancing infectivity, with statins reducing this spread and offering protection.

bioRxiv · Jun 30, 2020 · PreprintMicrobiology

A Macrophage Response To Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage In Leprosy

C. A. Madigan, C. Cambier, K. M. Kelly-Scumpia, P. O. Scumpia, T.-Y. Cheng, J. Zailaa, B. R. Bloom, D. B. Moody, S. T. Smale, A. Sagasti, R. L. Modlin, L. Ramakrishnan

The paper shows that M. leprae's PGL-1 toxin triggers macrophages to damage nerves by inducing nitric oxide, leading to axon demyelination in leprosy.

bioRxiv · Apr 17, 2017Microbiology