MicrobiologybioRxiv
A Macrophage Response To Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage In Leprosy
C. A. Madigan, C. Cambier, K. M. Kelly-Scumpia…·L. Ramakrishnan
The paper shows that M. leprae's PGL-1 toxin triggers macrophages to damage nerves by inducing nitric oxide, leading to axon demyelination in leprosy.