Revealing dynamic temporal trajectories and underlying regulatory networks with Cflows
X. Sun, S. Gupta, A. Tong, M. Kuchroo, D. Bhaskar, C. Liu, A. Venkat, B. Perez San Juan, L. Rangel, V. Rodriguez, J. G. Lock, C. Chaffer, S. Krishnaswamy
Cflows infers continuous cell state transitions and gene regulatory networks from static scRNA-seq data, revealing ESRRA as a key driver of tumor formation.
bioRxiv · Mar 28, 2023 · PreprintCancer Biology