Intragenic proviral elements support transcription of defective HIV-1 proviruses
J. Kuniholm, E. Armstrong, B. Bernabe, C. Coote, A. Berenson, S. Drinan, A. Olson, X. He, N. Lin, J. Fuxman Bass, A. J. Henderson
The paper shows defective HIV-1 proviruses can be transcribed via intragenic elements, producing aberrant RNAs that may contribute to inflammation in HIV-positive individuals.
bioRxiv · Sep 29, 2021Microbiology