First comprehensive identification of proteins with increased O-GlcNAc levels during pressure overload hypertrophy.
W. Z. Zhu, T. Palazzo, M. Zhou, H. M. Olson, L. Pasa-Tolic, A. Olson
The paper identifies 707 O-GlcNAcylated proteins in cardiac tissue during pressure overload hypertrophy, finding 233 significantly increased, with validation of CPT1B and PDH.
bioRxiv · Feb 17, 2022 · PreprintPhysiology