Author

C. DSantos

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Maiques-Diaz· 1 shared A. Moore· 1 shared A. Rosenwald· 1 shared C. S. Chilamakuri· 1 shared E. Gerhard-Hartmann· 1 shared I. Mohorianu· 1 shared I. Moutsoupoulos· 1 shared I. Ringshausen· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Maiques-Diaz

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1 paper

Recent·Most cited

NOTCH1 drives immune-escape mechanisms in B cell malignancies

M. Mangolini, A. Maiques-Diaz, S. Charalampopoulou, E. Gerhard-Hartmann, J. Bloehdorn, A. Moore, J. Lu, V. N. Roamio Franklin, C. S. Chilamakuri, I. Moutsoupoulos, A. Rosenwald, S. Stilgenbauer, T. Zenz, I. Mohorianu, C. DSantos, , I. Ringshausen

This study shows NOTCH1 mutations in B cell malignancies promote immune escape by upregulating PD-L1 and silencing HLA-class II, leading to poor clinical outcomes.

bioRxiv · Apr 10, 2021 · PreprintCancer Biology