Author

S. Stilgenbauer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Approach:experimental assay· 2 Assay:proteomics· 2

Frequent Co-Authors

T. Zenz· 3 shared J. Bloehdorn· 2 shared J. Lu· 2 shared M. Seifert· 2 shared M. Seiffert· 2 shared P. M. Roessner· 2 shared R. Kueppers· 2 shared S. Dietrich· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

T. Zenz

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5 papers

Recent·Most cited

A heterogeneous pool of tumor precursor cells with self-replenishing and tumor-originating properties in Chronic Lymphocytic Leukemia

B. Budeus, M. Dampmann, A. Kibler, B. Fassbender, M. Brauser, K. Bronischewski, E. Homp, S. Taudien, P. Johansson, J. Bloehdorn, S. Stilgenbauer, J. von Tresckow, J. Duerig, H. C. Reinhardt, R. Kueppers, , M. Seifert

The paper identifies a heterogeneous subpopulation of CLL-related B cells with self-replenishing and tumor-initiating properties that contribute to disease progression and clonal evolution.

bioRxiv · May 4, 2022 · PreprintCancer Biology

Proteogenomics refines the molecular classification of chronic lymphocytic leukemia

S. A. Herbst, M. Vesterlund, A. J. Helmboldt, R. Jafari, I. Siavelis, M. Stahl, E. Schitter, N. Liebers, B. Brinkmann, F. Czernilofsky, T. Roider, P.-M. Bruch, M. Iskar, A. Kittai, Y. Huang, , Hu

The paper performs a proteogenomic analysis of chronic lymphocytic leukemia, identifies a new poor-prognosis subgroup (ASB-CLL) through proteomic profiling, and links it to clinical outcomes.

bioRxiv · Mar 1, 2022Cancer Biology

NOTCH1 drives immune-escape mechanisms in B cell malignancies

M. Mangolini, A. Maiques-Diaz, S. Charalampopoulou, E. Gerhard-Hartmann, J. Bloehdorn, A. Moore, J. Lu, V. N. Roamio Franklin, C. S. Chilamakuri, I. Moutsoupoulos, A. Rosenwald, S. Stilgenbauer, T. Zenz, I. Mohorianu, C. DSantos, , I. Ringshausen

This study shows NOTCH1 mutations in B cell malignancies promote immune escape by upregulating PD-L1 and silencing HLA-class II, leading to poor clinical outcomes.

bioRxiv · Apr 10, 2021 · PreprintCancer Biology

EOMES and IL-10 regulate anti-tumor activity of PD-1+ CD4+ T-cells in B-cell Non-Hodgkin lymphoma

P. M. Roessner, L. LLaó Cid, E. Lupar, T. Roider, M. Bordas, C. Schifflers, A.-C. Gaupel, F. Kilpert, M. Krötschel, S. J. Arnold, L. Sellner, S. Stilgenbauer, S. Dietrich, P. Lichter, A. Izcue, M. Seiffert

bioRxiv · Mar 9, 2020Cancer Biology

Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL

J. A. Wierzbinska, R. Toth, N. Ishaque, K. Rippe, J.-P. Mallm, L. Klett, D. Mertens, T. Zenz, T. Hielscher, M. Seifert, R. Kueppers, Y. Assenov, P. Lutsik, S. Stilgenbauer, P. M. Roessner, , D. B. Lipka

This study introduces Methyl-COOM, a method to identify cell-of-origin and CLL-specific epigenetic aberrations by analyzing DNA methylation patterns.

bioRxiv · Feb 4, 2020Cancer Biology