BiochemistrybioRxiv
Emergence of a proton exchange-based isomerization and lactonization mechanism in the plant coumarin synthase COSY
C. Y. Kim, A. J. Mitchell, D. W. Kastner…·J.-K. Weng
This study identifies a proton exchange-based isomerization and lactonization mechanism in the plant enzyme COSY, revealing its unique catalytic activity and evolutionary adaptation.
DOI 10.1038/s41467-023-36299-1