Cell BiologybioRxiv
Steroid-resistant nephrotic syndrome associated MYO1E mutations have differential effects on myosin 1e localization, dynamics, and activity
P.-J. Liu, L. K. Gunther, D. Perez…·M. Krendel
This study investigates two MYO1E mutations in SRNS patients, showing T119I affects Myo1e localization and D388H reduces ATPase activity and actin translocation.
DOI 10.1681/asn.2021111505