Mycobacteria-specific CD4+IFN-γ+ cell expresses naïve-surface markers and confers superior protection against tuberculosis infection compared to central and effector memory CD4+ T cell subsets
S. Chatterjee, J. Yuan, J. Tenant, T. Pacatte, C. Eickhoff, A. Blazevic, D. Hoft
The paper identifies a novel Mycobacterium tuberculosis-specific CD4+IFN-γ+ T cell subset with naive-like markers that provides better protection against TB than central or effector memory T cells.
bioRxiv · Aug 16, 2018Immunology