Next generation SARM1 knockout and epitope tagged CRISPR-Cas9-generated isogenic mice reveal that SARM1 does not participate in regulating nuclear transcription, despite confirmation of protein expression in macrophages
C. G. Doran, R. Sugisawa, M. Carty, F. Roche, C. Fergus, K. Hokamp, V. P. Kelly, A. G. Bowie
This study generates SARM1 knockout and epitope-tagged mice to show SARM1 is expressed in macrophages but does not regulate transcription in these cells.
bioRxiv · Aug 25, 2021Immunology