Author

M. Carty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. G. Bowie· 2 shared R. Sugisawa· 2 shared A. Dumigan· 1 shared A. Kissenpfening· 1 shared B. Morris· 1 shared C. Fergus· 1 shared C. Feriotti· 1 shared C. G. Doran· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

A. G. Bowie

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Author profile →

2 papers

Recent·Most cited

Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity.

C. Feriotti, J. sa-Pessoa Graca Santos, R. Calderon-Gonzalez, L. Gu, B. Morris, R. Sugisawa, J. L. Insua, M. Carty, A. Dumigan, R. Ingram, A. Kissenpfening, A. G. Bowie, J. A. Bengoechea

This study shows Klebsiella pneumoniae uses SARM1, a host protein, to suppress immune responses via type I IFN signaling, enhancing its survival in macrophages.

bioRxiv · Sep 29, 2021Microbiology

Next generation SARM1 knockout and epitope tagged CRISPR-Cas9-generated isogenic mice reveal that SARM1 does not participate in regulating nuclear transcription, despite confirmation of protein expression in macrophages

C. G. Doran, R. Sugisawa, M. Carty, F. Roche, C. Fergus, K. Hokamp, V. P. Kelly, A. G. Bowie

This study generates SARM1 knockout and epitope-tagged mice to show SARM1 is expressed in macrophages but does not regulate transcription in these cells.

bioRxiv · Aug 25, 2021Immunology