MicrobiologybioRxiv
Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity.
C. Feriotti, J. sa-Pessoa Graca Santos, R. Calderon-Gonzalez…·J. A. Bengoechea
This study shows Klebsiella pneumoniae uses SARM1, a host protein, to suppress immune responses via type I IFN signaling, enhancing its survival in macrophages.
DOI 10.1016/j.celrep.2022.111167