Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in Drosophila prostate-like secondary cells
A. Sekar, A. Leiblich, J. E. E. U. Hellberg, D. Sarma, C. C. Mendes, M. S. Wainwright, C. Gandy, D. C. I. Goberdhan, F. C. Hamdy, C. Wilson
This study shows that Rbf/E2F1 and cell cycle regulators control growth and endoreplication in Drosophila secondary cells via steroid-independent EcR signalling, mirroring mechanisms in castration-resistant prostate cancer.
bioRxiv · Mar 27, 2021 · PreprintCell Biology