Author

F. C. Hamdy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. D. Lamb· 2 shared A. Lambert· 2 shared B. Vojnovic· 2 shared C. Verrill· 2 shared C. Wilson· 2 shared D. C. I. Goberdhan· 2 shared D. C. Wedge· 2 shared D. J. Woodcock· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

A. D. Lamb

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Novel Methylation Markers in a Prostate Cancer Cohort are Associated with Disease Development and Relapse

R. P. Lach, S. Pita, W.-K. Leung, A. Babbage, S. Merson, S. Hawkins, H. Luxton, J. Kay, H. C. Whitaker, D. J. Woodcock, V. Haberland, Z. Kote-Jarai, T. Milne-Clark, K. O'Neill, T. Brendler-Spaeth, , A. G. Lynch

The paper identifies novel methylation markers in a prostate cancer cohort associated with disease development and relapse, showing their predictive power for recurrence.

bioRxiv · Aug 27, 2026 · PreprintCancer Biology

Stress-induced Rab11a-exosomes induce AREG-mediated cetuximab resistance in colorectal cancer

J. D. Mason, E. Marks, S.-J. Fan, K. McCormick, C. Wilson, A. L. Harris, F. C. Hamdy, C. Cunningham, D. C. I. Goberdhan

This paper shows that stress-induced Rab11a-exosomes carrying AREG promote cetuximab resistance in colorectal cancer by activating EGFR signaling in KRAS-wild type cells.

bioRxiv · Dec 19, 2023 · PreprintCancer Biology

Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole genome sequencing with histopathological features

S. R. Rao, C. Verrill, L. Cerundolo, N. K. Alham, Z. Kaya, M. O'Hanlon, A. Hayes, A. Lambert, M. James, I. D. C. Tullis, J. Niederer, S. Lovell, A. Omer, F. Lopez, T. Leslie, , F. C. Hamdy

This study integrates multi-region whole genome sequencing with histopathological data to reconstruct tumour phylogenies and identify molecular steps in prostate cancer progression and metastasis.

bioRxiv · Feb 27, 2023Cancer Biology

Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in Drosophila prostate-like secondary cells

A. Sekar, A. Leiblich, J. E. E. U. Hellberg, D. Sarma, C. C. Mendes, M. S. Wainwright, C. Gandy, D. C. I. Goberdhan, F. C. Hamdy, C. Wilson

This study shows that Rbf/E2F1 and cell cycle regulators control growth and endoreplication in Drosophila secondary cells via steroid-independent EcR signalling, mirroring mechanisms in castration-resistant prostate cancer.

bioRxiv · Mar 27, 2021 · PreprintCell Biology

Tumor irradiation combined with vascular-targeted photodynamic therapy enhances anti-tumor effects in preclinical prostate cancer.

H. T. Sjoberg, Y. J. Philippou, A. L. Magnussen, I. D. Tullis, E. Bridges, A. Chatrian, J. Loefebvre, K. H. Tam, E. A. Murphy, J. Rittscher, D. Preise, L. Agemy, T. Yechezkel, S. C. Smart, P. Kinchesh, , R. J. Bryant

This paper investigates combining fractionated radiotherapy with vascular-targeted photodynamic therapy to enhance tumor control in preclinical prostate cancer models.

bioRxiv · Nov 26, 2020 · PreprintCancer Biology