Author

C. Hamilton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Olona· 1 shared C. E. Martina· 1 shared E. Elghonaimy· 1 shared G. Larrouy-Maumus· 1 shared H. Antelmann· 1 shared I. Gonzalez· 1 shared J. Meiler· 1 shared K. L. Swancutt· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. Olona

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Simultaneous selection of nanobodies for accessible epitopes on immune cells in the tumor microenvironment

T. V. Sekar, E. Elghonaimy, K. L. Swancutt, S. Diegeler, I. Gonzalez, C. Hamilton, P. Q. Leung, J. Meiler, C. E. Martina, M. Whitney, T. A. Aguilera

This study introduces INSPIRE-seq, a method to identify nanobodies targeting immune cells in the tumor microenvironment, revealing a dendritic cell-binding nanobody that interacts with PHB2.

bioRxiv · May 26, 2021Bioengineering

Phosphatidylinositol Acyl Chains Configure Priming and Activation of the NLRP3 Inflammasome

C. Hamilton, A. Olona, S. Leishman, K. MacDonald-Ramsahai, S. Cockcroft, G. Larrouy-Maumus, P. K. Anand

This study shows that PI acyl chains regulate NLRP3 inflammasome priming and activation in mouse macrophages through effects on TIRAP and NLRP3 phosphorylation.

bioRxiv · Jan 14, 2020Immunology

Staphylococcus aureus uses the bacilliredoxin (BrxAB)/bacillithiol disulfide reductase (YpdA) redox pathway to defend against oxidative stress under infections

N. Linzner, V. V. Loi, V. N. Fritsch, Q. N. Tung, S. Stenzel, M. Wirtz, R. Hell, C. Hamilton, K. Tedin, M. Fulde, H. Antelmann

This study identifies the BrxAB/BSH/YpdA pathway as critical for S. aureus to manage oxidative stress and survive infections by maintaining BSH redox homeostasis.

bioRxiv · May 1, 2019Microbiology