ImmunologybioRxiv
Phosphatidylinositol Acyl Chains Configure Priming and Activation of the NLRP3 Inflammasome
C. Hamilton, A. Olona, S. Leishman…·P. K. Anand
This study shows that PI acyl chains regulate NLRP3 inflammasome priming and activation in mouse macrophages through effects on TIRAP and NLRP3 phosphorylation.
DOI 10.4049/immunohorizons.2200058