Author

S. Leishman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

P. K. Anand· 2 shared S. Cockcroft· 2 shared A. Olona· 1 shared C. Hamilton· 1 shared G. Larrouy-Maumus· 1 shared J. Behmoaras· 1 shared K. MacDonald-Ramsahai· 1 shared L. Qian· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

P. K. Anand

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2 papers

Recent·Most cited

Fatty acid synthesis promotes inflammasome activation through NLRP3 palmitoylation.

S. Leishman, N. M. Aljadeed, L. Qian, S. Cockcroft, J. Behmoaras, P. K. Anand

This study shows that fatty acid synthesis promotes NLRP3 inflammasome activation through palmitoylation of NLRP3, with no effect on AIM2 inflammasome activation.

bioRxiv · Oct 30, 2023Immunology

Phosphatidylinositol Acyl Chains Configure Priming and Activation of the NLRP3 Inflammasome

C. Hamilton, A. Olona, S. Leishman, K. MacDonald-Ramsahai, S. Cockcroft, G. Larrouy-Maumus, P. K. Anand

This study shows that PI acyl chains regulate NLRP3 inflammasome priming and activation in mouse macrophages through effects on TIRAP and NLRP3 phosphorylation.

bioRxiv · Jan 14, 2020Immunology