BiophysicsbioRxiv
Mutational analysis of the structure and function of the chaperone domain of UNC-45B
I. Gaziova, T. Moncrief, C. J. Christian…·A. F. Oberhauser
This paper investigates the chaperone function of UNC-45B's UCS domain by engineering mutations and analyzing their effects on structure, stability, and sarcomere organization in C. elegans and human cataract.
DOI 10.1016/j.bpj.2020.07.012