ImmunologybioRxiv
Modelling the interplay between the CD4+/CD8+ T-cell ratio and the expression of MHC-I in tumours
C. J. Hurry, A. Mozeika, A. Annibale
The paper develops a mathematical model to show how the CD4+/CD8+ T-cell ratio, MHC-I expression, and T-cell infiltration interact in tumour elimination.
DOI 10.1007/s00285-021-01622-1