Energy-dependent transport at dural lymphatic vessels is necessary for Aβ brain clearance in Alzheimer's disease
L. Romanova, H. Philips, G. Calip, K. Hauser, D. Peterson, O. Lazarov, D. Predescu, S. Predescu, J. Schneider, J. Kordower, E. Hansen, C. Lam, C. Janson
The paper shows that energy-dependent transport in dural lymphatic vessels is critical for clearing Aβ in Alzheimer's disease, and blocking this pathway accelerates Aβ pathology.
bioRxiv · Feb 5, 2019 · PreprintBiochemistry