Enhanced cell viscosity: a new phenotype associated withlamin A/C alterations
C. Jebane, A.-A. Varlet, M. Karnat, L. M. Hernandez-Cedillo, A. Lecchi, F. Bedu, C. Desgrouas, C. Vigouroux, M.-C. Vantyghem, A. Viallat, J.-F. Rupprecht, E. Helfer, C. Badens
This study quantifies whole cell mechanical changes caused by lamin A/C alterations using microfluidic experiments, revealing increased long-time viscosity as a potential diagnostic marker.
bioRxiv · Jul 18, 2022Biophysics