BiophysicsbioRxiv
Mechanical stress driven by rigidity sensing governs epithelial stability
S. Sonam, L. Balasubramaniam, S.-Z. Lin…·B. Ladoux
The paper shows that substrate stiffness drives mechanical switches in epithelial monolayers, leading to stochastic failure through topological defects.
DOI 10.1038/s41567-022-01826-2