Y. Toyama

This study identifies a Golgi-dependent pathway involving Arf1 and Sec71 that regulates microtubule growth and reactivates quiescent neural stem cells in Drosophila.

The paper shows that substrate stiffness drives mechanical switches in epithelial monolayers, leading to stochastic failure through topological defects.

The paper identifies that spatial inhomogeneity in mechanotransduction via YAP drives compensatory proliferation in response to apoptosis.

The paper identifies gene expression as a key factor driving parallel evolution of herbicide resistance in Monochoria vaginalis by showing higher expression of specific ALS gene copies.

The paper investigates how epithelial cell monolayers switch from extensile to contractile behavior as intercellular contacts weaken, revealing mechanotransductive responses and implications for cell sorting and tissue dynamics.

This study identifies a dual-mode actin mechanism involving lamellipodia protrusions and purse-string contractility that drives apoptotic cell extrusion in epithelia.

This study shows that desmosomal junctions remain intact during apoptotic cell extrusion and are crucial for the process, with actomyosin cables interacting mechanically with desmosomes.

This study shows that PTP1B inhibition combined with grating topography enhances endothelialization by remodeling endothelial adherens junctions and improving cell migration and proliferation.

The paper investigates the mechanical role of vinculin/β-catenin interaction in adherens junctions, showing that vinculin forms a direct structural connection with β-catenin to support mechanical tension and stabilize complexes.