Author

E. Helfer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Assay:imaging· 1

Frequent Co-Authors

A. CHARRIER· 2 shared A. Viallat· 2 shared A. Joly· 1 shared A. Lecchi· 1 shared A. Moreau· 1 shared A. Surendranath· 1 shared A.-A. Varlet· 1 shared B. Dehapiot· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

A. CHARRIER

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Substrate Stiffness Reshapes Layer Architecture and Biophysical Features of Human Induced Pluripotent Stem Cells to Modulate their Differentiation Potential

J. LLEWELLYN, A. CHARRIER, E. HELFER, R. DONO

This study shows that substrate stiffness affects hiPSC layer structure and biophysical properties, enhancing mesendoderm differentiation on softer substrates.

bioRxiv · Feb 1, 2024 · PreprintCell Biology

Physical mechanisms of red blood cell splenic filtration

A. Moreau, F. Yaya, H. Lu, A. Surendranath, A. Charrier, B. Dehapiot, E. Helfer, A. Viallat, Z. Peng

This paper investigates how red blood cells pass through narrow splenic slits using multiscale modeling, live imaging, and microfluidic experiments, finding that cells deform into two tether-connected spheres and unfold their cytoskeleton to pass through.

bioRxiv · Jan 10, 2023Biophysics

Talin and kindlin cooperate to control the density of integrin clusters.

J. Pernier, M. Cardoso Dos Santos, M. Souissi, A. Joly, H. Narassimprakash, O. Rossier, G. Giannone, E. Helfer, K. Sengupta, C. Le Clainche

This study shows that talin and kindlin work together to control integrin cluster density, with kindlin enhancing talin and integrin density and facilitating cluster segregation by actomyosin.

bioRxiv · Oct 7, 2022 · PreprintBiochemistry

Enhanced cell viscosity: a new phenotype associated withlamin A/C alterations

C. Jebane, A.-A. Varlet, M. Karnat, L. M. Hernandez-Cedillo, A. Lecchi, F. Bedu, C. Desgrouas, C. Vigouroux, M.-C. Vantyghem, A. Viallat, J.-F. Rupprecht, E. Helfer, C. Badens

This study quantifies whole cell mechanical changes caused by lamin A/C alterations using microfluidic experiments, revealing increased long-time viscosity as a potential diagnostic marker.

bioRxiv · Jul 18, 2022Biophysics