Author

C. K. Guegler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

M. T. Laub· 2 shared P. H. Culviner· 1 shared S. Srikant· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 2 mutual co-author links

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2 shared papersMicrobiology

M. T. Laub

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2 papers

Recent·Most cited

MicrobiologybioRxivApr 14, 2022

The evolution of a counter-defense mechanism in a virus constrains its host range

S. Srikant, C. K. Guegler, M. T. Laub

This study experimentally evolves T4 phage to overcome E. coli's toxin-antitoxin system, revealing a trade-off where counter-defense mechanisms constrain host range.

DOI 10.7554/elife.79549

E. colibacteria (other)

𝕏 PostBluesky

MicrobiologybioRxivJan 6, 2020

A simple, cost-effective, and robust method for rRNA depletion in RNA-sequencing studies

P. H. Culviner, C. K. Guegler, M. T. Laub

This paper develops a cost-effective method for rRNA depletion in RNA-seq by designing biotinylated oligonucleotides, achieving 75-80% mRNA reads and comparable results to the discontinued Ribo-Zero kit.

DOI 10.1128/mbio.00010-20

bacteria (other)bulk RNA-seq

𝕏 PostBluesky