Variable dose analysis: A novel RNAi-based method for detection of synthetic lethal interactions
B. E. Housden, Z. Li, C. Kelley, Y. Wang, Y. Hu, A. J. Valvezan, B. D. Manning, N. Perrimon
This paper introduces a novel RNAi-based method called variable dose analysis (VDA) to detect synthetic lethal interactions, identifying four FDA-approved drugs for TSC-related tumors.
bioRxiv · Aug 16, 2017Cancer Biology