Author

A. J. Valvezan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

B. D. Manning· 2 shared B. E. Housden· 1 shared C. Kelley· 1 shared E. P. Henske· 1 shared J. M. Asara· 1 shared M. C. McNamara· 1 shared M. E. Torrence· 1 shared N. Perrimon· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

B. D. Manning

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2 papers

Recent·Most cited

Cancer BiologybioRxivNov 11, 2019

IMPDH inhibitors for anti-tumor therapy in tuberous sclerosis complex

A. J. Valvezan, S. K. Miller, M. C. McNamara…·B. D. Manning

This paper evaluates IMPDH inhibitors for anti-tumor therapy in TSC, finding mizoribine more effective than mycophenolic acid in targeting mTORC1-driven tumors.

DOI 10.1172/jci.insight.135071

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivAug 16, 2017

Variable dose analysis: A novel RNAi-based method for detection of synthetic lethal interactions

B. E. Housden, Z. Li, C. Kelley…·N. Perrimon

This paper introduces a novel RNAi-based method called variable dose analysis (VDA) to detect synthetic lethal interactions, identifying four FDA-approved drugs for TSC-related tumors.

DOI 10.1073/pnas.1713362114

humanbulk RNA-seq

𝕏 PostBluesky