Author

C. Kharas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. R. Leferts· 1 shared C. E. Wobus· 1 shared C. M. Bassis· 1 shared D. Huynh· 1 shared G. Nunez· 1 shared J. Katta· 1 shared J. L. Platt· 1 shared M. Cascalho· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. R. Leferts

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1 paper

Recent·Most cited

Natural IgA and TNFRSF13B polymorphism: a double edged sword fueling balancing selection

J. L. Platt, M. G. de Mattos Barbosa, D. Huynh, A. R. Leferts, J. Katta, C. Kharas, P. Freddolino, C. M. Bassis, C. E. Wobus, R. Geha, R. J. Bram, G. Nunez, N. Kamada, M. Cascalho

The paper investigates how a dominant-negative variant of TNFRSF13B confers resistance to enteric pathogens by reducing natural IgA, suggesting balancing selection due to its dual role in immunity and pathogenesis.

bioRxiv · Jan 29, 2021 · PreprintImmunology