Author

C. L. Williams

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Assay:metagenomics· 2 Organism:C. elegans· 1

Frequent Co-Authors

R. Tamayo· 2 shared A. A. Bertuch· 1 shared A. N. Edwards· 1 shared A. N. Meredith· 1 shared A. R. Ybarra· 1 shared A. Sheen· 1 shared B. S. Durrant· 1 shared C. Condon· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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2 shared papersMicrobiology

R. Tamayo

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Environmental change drives multi-generational shifts in the gut microbiome that mirror changing animal fitness

C. L. Williams, C. E. Williams, S. N. King, D. M. Shier

This study tracks how the gut microbiome and host fitness of Pacific pocket mice change across generations in captivity, finding that microbiomes stabilize after two to three generations and correlate with reproductive success.

bioRxiv · Oct 24, 2023 · PreprintEcology

Hyperextended telomeres promote C-circle formation in telomerase positive human cells

C. Y. Jones, C. L. Williams, S. P. Moreno, D. K. Morris, C. Mondello, J. Karlseder, A. A. Bertuch

This study shows that hyperextended telomeres in telomerase-positive cells promote C-circle formation, independent of telomerase activity and replication stress, suggesting C-circles are not exclusive to ALT.

bioRxiv · Jan 26, 2023Cancer Biology

Ablative radiotherapy improves survival in autochthonous cancer mouse models

D. R. Schmidt, I. M. T. Gramatikov, A. Sheen, C. L. Williams, M. Hurwitz, L. E. Dodge, E. Holupka, W. S. Kiger, M. R. Cornwall-Brady, W. Huang, H. H. Mak, K. Cormier, C. Condon, D. Wittrup, O. H. Yilmaz, , M. G. Vander Heiden

This study shows that ablative radiotherapy improves survival in autochthonous cancer mouse models and synergizes with androgen deprivation in prostate cancer.

bioRxiv · Jul 1, 2022 · PreprintCancer Biology

c-di-GMP inhibits early sporulation in Clostridioides difficile

A. N. Edwards, C. L. Williams, N. Pareek, S. M. McBride, R. Tamayo

This study shows that c-di-GMP inhibits early sporulation in C. difficile by reducing sporulation frequency and gene transcription, suggesting a regulatory role in spore formation.

mSphere · Dec 22, 2021Peer-reviewedMicrobiology

Flagellum and toxin phase variation impacts intestinal colonization and disease development in a mouse model of Clostridioides difficile infection

D. Trzilova, M. A. H. Warren, N. C. Gadda, C. L. Williams, R. Tamayo

This study shows that flagellum and toxin phase variation in C. difficile affects intestinal colonization and disease development in mouse models.

bioRxiv · Sep 29, 2021Microbiology

Gut microbiota and phytoestrogen-associated infertility in southern white rhinoceros

C. L. Williams, A. R. Ybarra, A. N. Meredith, B. S. Durrant, C. W. Tubbs

The paper investigates the relationship between gut microbiota, phytoestrogens, and fertility in southern white rhinoceros, finding that phytoestrogen profiles and microbial taxa influence reproductive outcomes.

bioRxiv · Oct 24, 2018Microbiology