Author

C. Lien

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

S. Liu· 2 shared T. Wang· 2 shared C.-K. Chou· 1 shared P. Selvaraj· 1 shared P. Selveraj· 1 shared W. W. Wu· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

S. Liu

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2 papers

Recent·Most cited

The PRRA insert at the S1/S2 site modulates cellular tropism of SARS-CoV-2 and ACE2 usage by the closely related Bat raTG13

S. Liu, P. Selvaraj, C. Lien, W. W. Wu, C.-K. Chou, T. Wang

This study shows that the PRRA insert in SARS-CoV-2 and raTG13 Spike proteins affects ACE2 usage across species, altering cellular tropism.

bioRxiv · Jul 20, 2020Microbiology

Evaluation of 19 antiviral drugs against SARS-CoV-2 Infection

S. Liu, C. Lien, P. Selveraj, T. Wang

This study evaluates 19 antiviral drugs against SARS-CoV-2 infection and finds remdesivir to be the most effective, while others show limited or no direct antiviral activity.

bioRxiv · Apr 29, 2020 · PreprintMicrobiology