Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumors
L. Zhu, J. L. Narloch, S. Onkar, M. Joy, C. Luedke, A. Hall, R. Kim, K. Pogue-Geile, S. Sammons, N. Nayyar, U. Chukwueke, P. K. Brastianos, C. K. Anders, A. C. Soloff, D. A. Vignali, , A. V. Lee
The paper compares immune cell infiltration in primary and metastatic breast tumors, finding reduced immune cell abundance but increased M2-like macrophages in metastases.
bioRxiv · Jan 20, 2019Immunology