BiochemistrybioRxivPreprint
Deglutarylation of GCDH by SIRT5 controls lysine metabolism in mice
D. P. Bhatt, C. A. Mills, K. A. Anderson…·M. D. Hirschey
This study identifies glutarylation of GCDH by glutaryl-CoA and shows SIRT5 deglutarylates GCDH, restoring its function and regulating lysine metabolism in mice.
DOI 10.1101/2020.06.28.176677