Author

C. M. Melo

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Crozier· 1 shared F. P. Saggioro· 1 shared J. A. Squire· 1 shared J. Bayani· 1 shared L. P. Chavez· 1 shared R. B. dos Reis· 1 shared S. Bonatto· 1 shared W. Lautert-Dutra· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

C. Crozier

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintApr 16, 2022

Quantitative MHC class-I/-II gene expression levels in CDK12 mutated prostate cancer reveal intratumorally T cell adaptive immune response in tumors

W. Lautert-Dutra, C. M. Melo, L. P. Chavez…·J. A. Squire

The paper examines MHC expression levels in CDK12 mutated prostate cancer and finds that higher MHC expression correlates with immune activation and T cell infiltration, while lower MHC expression is linked to genomic loss of heterozygosity and reduced immune response.

DOI 10.1101/2022.04.16.487364

humanbulk RNA-seq

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