Author

C. McDermott-Roe

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

A. Hoshino· 1 shared K. Musunuru· 1 shared W. Lv· 1 shared Y. Shao· 1 shared Z. Arany· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

A. Hoshino

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1 paper

Recent·Most cited

CRISPR/Cas9 screens implicate RARA and SPNS1 in doxorubicin cardiotoxicity

W. Lv, Y. Shao, A. Hoshino, Z. Arany, K. Musunuru, C. McDermott-Roe

This study uses CRISPR/Cas9 screens to identify RARA and SPNS1 as genetic modifiers of doxorubicin cardiotoxicity, revealing their roles in cell death and drug accumulation.

bioRxiv · Aug 1, 2022 · PreprintCell Biology