Evolution of resistance to KRASG12C inhibitor in a non-small cell lung cancer responder
J. Xu, S. Wang, Z. Wang, J. Huang, C. Xie, Y. Cao, C. Ming, E. L.-H. Leung
This study tracks immune cell changes in a KRASG12C NSCLC patient during sotorasib treatment and resistance, showing fluctuations in CD8+CD161hi T cells.
bioRxiv · Dec 18, 2023Cancer Biology