Author

C. Mowbray

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Assay:proteomics· 1

Frequent Co-Authors

E. Chatelain· 2 shared F. Escudie· 2 shared I. Scandale· 2 shared A. Ali· 1 shared A. Finzi· 1 shared A. M. Z. Tan· 1 shared B. Weynand· 1 shared C. Harding· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

E. Chatelain

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice

I. Ullah, F. Escudie, I. Scandale, Z. Gilani, G. Gendron-Lepage, F. Gaudette, C. Mowbray, L. Fraisse, R. Bazin, A. Finzi, W. Mothes, P. Kumar, E. Chatelain, P. D. Uchil

This study evaluates DAAs and their combinations for SARS-CoV-2 clearance in mice, finding that dual-targeting regimens outperform monotherapies.

bioRxiv · May 31, 2023 · PreprintMicrobiology

Evasion of Toll-like Receptor Recognition by Escherichia coli is mediated via Population Level Regulation of Flagellin Production

M. Lanz, C. M. Birchall, L. K. Drage, D. M. Picton, C. Mowbray, Q. Alsenani, A. M. Z. Tan, A. Ali, C. Harding, R. Pickard, J. Hall, P. D. Aldridge

This study shows that uropathogenic E. coli evades TLR5 recognition by regulating flagellin production at the population level, not through antigenic variation.

bioRxiv · Nov 18, 2021 · PreprintMicrobiology

The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern

R. Abdelnabi, C. S.-Y. Foo, D. Jochmans, L. Vangeel, S. De Jonghe, P. Augustijns, R. Mols, B. Weynand, T. Wattanakul, R. Hoglund, J. Tarning, C. Mowbray, P. Sjo, F. Escudie, I. Scandale, , J. Neyts

PF-07321332, an oral protease inhibitor, effectively protects Syrian hamsters against SARS-CoV-2 variants of concern, including beta and delta, by preventing infection and transmission.

bioRxiv · Nov 4, 2021Microbiology