I. Ullah

Artemisinin resistance mutations in Pfcoronin impede hemoglobin uptake

This study identifies Pfcoronin mutations as a mechanism of artemisinin resistance by impairing hemoglobin uptake in Plasmodium falciparum.

Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice

This study evaluates DAAs and their combinations for SARS-CoV-2 clearance in mice, finding that dual-targeting regimens outperform monotherapies.

The Src and Abl family kinases activate the Spleen Tyrosine Kinase to maximize phagocytosis and Leishmania infection

This study shows that Src and Abl family kinases activate SYK to enhance Leishmania uptake by macrophages, leading to increased disease in mice.

Molecular basis for antiviral activity of pediatric neutralizing antibodies targeting SARS-CoV-2 Spike receptor binding domain

This study identifies two potent neutralizing antibodies, EH3 and EH8, from a pediatric patient that cross-neutralize SARS-CoV-2 variants and provide in vivo protection against the Delta VOC.

The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice

This study shows that CCPs with high Fc-effector activity, rather than just neutralizing ability, are more effective in treating SARS-CoV-2 in mice.

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

The paper develops ACE2-Fc molecules that neutralize SARS-CoV-2 and show Fc-effector activity, effectively treating lethal infection in mice.

Distribution And Population Of Chukar Partrigde (Alectoris chukar) In District Bajuar, KPK, Pakistan

This study examines the distribution and population of Chukar Partridges in Bajaur District, KPK, Pakistan, identifying habitat threats and activity patterns.

An anti-SARS-CoV-2 non-neutralizing antibody with Fc-effector function defines a new NTD epitope and delays neuroinvasion and death in K18-hACE2 mice

Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern

This study characterizes two SARS-CoV-2 antibodies effective against variants, showing their structural basis and mechanisms of neutralization.

Genomic miscellany and allelic frequencies of Plasmodium falciparum msp-1, msp-2 and glurp in parasite isolates

This study analyzes genetic diversity and allelic frequencies of msp-1, msp-2, and glurp in P. falciparum isolates from Pakistan, finding high genetic diversity and significant correlation between MOI and parasite density for msp-2.

Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy

This study uses live imaging to show that neutralizing antibodies against SARS-CoV-2 need both Fab and Fc functions to effectively prevent and resolve infection in mice.

In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission

This study uses in vivo imaging to show that Siglec-1/CD169 on sentinel macrophages facilitates retrovirus transmission through multiple routes.

An in vitro assessment of anti-SARS-CoV-2 activity of oral preparations of iodine complexes (RENESSANS)

This study assesses the in vitro anti-SARS-CoV-2 activity of iodine complex oral formulations, finding that higher concentrations show significant inhibition of viral replication and cytopathic effects.

Bacteriophages can be used as infection control agents: A proof-of concept study involving anti-Acinetobacter baumannii phage

This study demonstrates that bacteriophages can effectively reduce XDR Acinetobacter baumannii on solid surfaces, serving as a potential infection control agent.