Cancer BiologybioRxivPreprint
Analysis of Skin Cancers from Xeroderma Pigmentosum Patients Reveals Heterogeneous UV-Induced Mutational Profiles Shaped by DNA Repair
A. A. Yurchenko, F. Rajabi, T. Braz-Petta…·S. I. Nikolaev
The paper analyzes skin cancer genomes from Xeroderma Pigmentosum patients to show how NER activity shapes mutation rates and reveals POLH's role in bypassing UV-induced DNA lesions.
DOI 10.1101/2022.10.14.512263