Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation
V. E. B. Hipolito, J. Diaz, K. Tandoc, C. Oertlin, J. Ristau, N. Chauhan, A. Saric, S. McLaughlan, O. Larsson, I. Topisirovic, R. Botelho
This study identifies mTORC1-dependent translation as a mechanism for endo-lysosome expansion and antigen presentation during phagocyte activation.
bioRxiv · Nov 13, 2019Cell Biology