REL deregulation stands as a primary hit for AID-imprinted B-cells along the germinal center competition
L. Prevaud, C. Vincent-Fabert, T. Marchiol, Q. Lemasson, C. Ouk, C. Carrion, M. Cogne, J. Feuillard, N. Faumont
This study shows REL deregulation gives AID-imprinted B-cells a competitive advantage in germinal centers, promoting expansion and potential transformation into aggressive lymphomas.
bioRxiv · Oct 10, 2023 · PreprintCancer Biology