Author

C. R. McCutcheon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

D. M. Aronoff· 2 shared J. Gaddy· 2 shared S. D. Manning· 2 shared M. G. Petroff· 1 shared M. Petroff· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 9 mutual co-author links

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2 shared papersImmunology

D. M. Aronoff

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 10, 2022

Group B streptococcal membrane vesicles induce proinflammatory cytokine production and are sensed in an NLRP3 inflammasome-dependent mechanism in human macrophages

C. R. McCutcheon, J. Gaddy, D. M. Aronoff…·M. G. Petroff

This study shows that GBS membrane vesicles induce proinflammatory cytokines in macrophages via NLRP3 inflammasome-dependent mechanisms, suggesting potential for immunotherapeutic targeting.

DOI 10.1101/2022.08.10.503555

humanproteomics

𝕏 PostBluesky

MicrobiologybioRxivAug 24, 2021

Production and composition of group B streptococcal membrane vesicles varies across diverse lineages

C. R. McCutcheon, J. Gaddy, D. M. Aronoff…·S. D. Manning

This study quantifies membrane vesicle production and protein composition across diverse GBS strains, finding lineage-dependent variation in MVs that may influence clinical outcomes.

DOI 10.3389/fmicb.2021.770499

virusproteomics

𝕏 PostBluesky