C. R. Sanders

This paper develops ANN models to predict the functional impact of KCNQ1 variants using biophysical features, outperforming models based solely on evolutionary features.

This paper describes the delivery of SARS-CoV-2 envelope protein into human cells using amphipols, enabling membrane integration and retrograde trafficking to ERGIC and Golgi regions.

This paper shows that PMP22 preferentially partitions into ordered membrane domains, and disease mutations disrupt this preference.

This paper develops and validates structural models of human KCNQ1 potassium channels to understand mutation-induced dysfunction and guide drug design.